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Editor,
The Journal of Integrative Medicine
Formerly, Associate Professor of Pathology (adj.), College
of Physicians
and Surgeons of Columbia University, NY
Formerly, President of Staff and Chief Pathologist,
Holy Name Hospital, Teaneck, NJ
Fellow, Royal
College of Surgeons of England -
Diplomate,
American Board of Anatomic and Clinical Pathology
Diplomate, American Boards of Environmental Medicine
Past President Capital University of Integrative
Medicine |
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The Aging Healthfully Virtual Library
- The Works of Majid Ali, M.D.
__________________________________________________________________
Articles from Aging Healthfully Magazine
The data in this clinical outcome study document the
efficacy of the
ecologic-integrative management protocols used in reversing fibromyalgia
(excellent or good outcome in 84.7%).
A Clinical Study:
POSITIVE RESULTS ACHIEVED
IN 150 FIBROMYALGIA PATIENTS!
Abstract from The Journal of Integrative Medicine Volume 3 Number 1
Majid Ali, M.D., Judy Juco, M.D., Alfred O. Fayemi, M.D., Omar Ali, M.D., Mahboob
Baig, M.B.,B.S.;
Marta Babol, M.D., Karimullah Zirvi, Ph.D., Carol Grieder-Bradenberger,
R.N., Mary Ann Carroll, R.N.
___________________________________________________________________________________
EFFICACY OF ECOLOGIC-INTEGRATIVE MANAGEMENT
PROTOCOLS FOR REVERSAL OF FIBROMYALGIA:
An Open Prospective Study of 150 Patients
Objective
To report the results of an open, prospective trial of broad-based,
ecologic-integrative management protocols for the reversal of fibromyalgia in 150
patients.
Patients
One hundred fifty patients who presented at the Institute of
Integrative Medicine with fibromyalgia and for whom clinical outcome data were available
for at least six months prior were included in this study. There were 116 females (range
of age, 13-81 yrs) and 34 males (range of age, 14-68 yrs). The average duration of illness
was 6.6 years and the average duration of clinical management was 11.5 months. Patients
were divided into three groups: Group 1, when the duration of illness was less than three
years; Group 2, when the duration of illness was between three and six years; and Group 3,
when the duration of illness was longer than six years.
Ecologic-Integrative Management Protocols
The comprehensive, ecologic-integrative management protocols employed
were based on clinical, biochemical, and high-resolution microscopic assessment of the
microecologic cellular and macroecologic tissue-organ systems of the body. Such protocols
included the following: choices in the kitchen designed to provide for optimal hydration,
elimination of foods causing incompatibility reactions and rapid
glucose-insulin-adrenaline shifts; supplementation with vitamins, minerals, and some
"redox-restorative substances" (RRSs) such as glutathione, taurine,
methylsulfonylmethane (MSM), coenzyme Q10, and lipoic acid; ample herbal support for the
bowel, blood, and liver ecosystems (including colon hydrotherapy and liver flushes);
endocrine support, especially for the thyroid,
adrenals, and sex hormones; intramuscular
and intravenous nutrient protocols; oxygenative therapies, including nasal oxygen,
intravenous infusions of hydrogen peroxide and ozone, and EDTA chelation; gentle
stretching and noncompetitive (limbic) exercise; and training in effective methods for
self- regulation, stress reduction, and guidance for spiritual surrender.
Assessment of Compliance
Assessment of compliance was based on entries made on a specifically
designed clinical outcome sheet during follow-up visits. The following scale of scores was
used for assessment of compliance according to predetermined criteria: Class A, a
compliance value greater than 75%; Class B, a value between 75% and 50 %; Class C, a value
between 50% and 25%; and Class D, a value lower than 25%.
Assessment of Clinical Outcome
Assessment of clinical outcome was based on concurrent evaluation of
the progress made, or lack thereof, employing the clinical outcome sheet. The scale of
scores for clinical improvement comprised the following: excellent outcome (Category I)
when more than 90% relief of symptoms was obtained and all drug therapies were
discontinued; good outcome (Category II) when the relief of symptoms was between 90% and
75%, with a similar reduction in use of drugs; fair outcome (Category III) when the relief
of symptoms was between 75% and 50% with a similar reduction in symptoms; and poor outcome
(Category IV) when the relief of symptoms was less than 50% with a similar reduction in
the use of drugs.
Results
The overall final outcome scores for all 150 patients were as follows:
excellent outcome, 65.4%; good, 19.3%; fair, 5.3%; and poor, 10%. The final outcome scores
for Group 1 (56) patients were as follows: excellent outcome, 75%; good, 10.7%; fair,
7.2%; and poor, 7.1%. The final outcome scores for Group 2 patients (26) were as follows:
excellent outcome, 69.2%; good, 19.2%; fair, 7.7%; and poor, 3.9%. The final outcome
scores for Group 3 patients (68) were as follows: excellent outcome, 55.9%; good, 26.5%;
fair, 2.9 %; and poor, 14.7%.
Conclusion
The data in this clinical outcome study document the efficacy of the
ecologic-integrative management protocols used in reversing fibromyalgia (excellent or
good outcome in 84.7%). The results provide empirical support for the view that
fibromyalgia is an oxidative-dysoxygenative disorder (ODD) and that disruptions of the
bowel, blood, and liver ecosystems play critical roles in its pathogenesis. The data also
warrant further and larger clinical outcome studies of the efficacy of the
ecologic-integrative protocols such as those employed in this study for reversing
fibromyalgia, a disorder for which no pharmacologic regimens have yielded satisfactory
results so far.
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